Bone loss is a serious problem for astronauts and they do rigourous daily exercise to reduce the hazard. The International Space Station is equipped with a treadmill that astronauts have to use for about an hour a day. When the TVIS (treadmill vibration with isolation system – there is an acronym for everything) is used, vibration is generated that transmits through the space station and can affect vibration sensitive equipment and experiments.
Read more on the NASA research web site.